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. 2018 Feb 8;13(2):e0192194. doi: 10.1371/journal.pone.0192194

Table 3. Kinetic parameters of anti-FGFR2 scFv fragments.

Antibody name KD (M)a kon (1/Ms)a koff (1/s)a
scFvD8 1.4 2x 10−7 5.39 x 104 7.65 x 10−3
scFvF7 3.70 x 10−8 1.06 x 105 3.99 x 10−3
scFvG3 5.93 x 10−8 9.86 x 104 5.85 x 10−3
scFvG9 7.60 x 10−8 7.12 x 104 5.43 x 10−3
scFvH6 3.85 x 10−7 2.53 x 104 9.75 x 10−3

a Measured on the BIAcore3000 instrument. Kinetic constants were calculated with the BIA evaluation 4.1 software. Fitting error for global KD fit was below 2,5%.