Table 3. Multivariable adjusted comparisons of the rates of opioid and non-opioid utilization among exposed patients.
| Opioid Ratea | Opioid Rate Ratio (95% CI) |
Non-opioid Ratea | Non-opioid Rate Ratio (95% CI) |
||
|---|---|---|---|---|---|
| Gender | |||||
| Female | 327.1 | 1.19 (1.11, 1.28)* | 340.9 | 0.99 (0.93, 1.04) | |
| Male | 274.5 | Reference | 345.3 | Reference | |
| Age, years | |||||
| <1 | 301.8 | 1.37 (1.21, 1.55)* | 275.0 | 0.93 (0.85, 1.02) | |
| 1 to < 5 | 209.3 | Reference | 295.1 | Reference | |
| 5 to <10 | 234.0 | 1.04 (0.91, 1.17) | 365.6 | 1.24 (1.12, 1.37) | |
| 10 to <15 | 319.8 | 1.42 (1.26, 1.59)* | 390.5 | 1.32 (1.20, 1.46) | |
| 15 to <20 | 445.4 | 1.84 (1.66, 2.03)* | 410.2 | 1.39 (1.24, 1.56) | |
| Race | |||||
| White | 333.4 | Reference | 347.5 | Reference | |
| Black | 312.1 | 0.94 (0.85, 1.03) | 327.8 | 0.94 (0.87, 1.02) | |
| Asian | 255.4 | 0.76 (0.61, 0.95)* | 345.4 | 0.99 (0.90, 1.10) | |
| Other | 303.4 | 0.91 (0.82, 1.01) | 352.1 | 1.01 (0.96, 1.07) | |
| Insurance | |||||
| Private | 292.4 | Reference | 328.2 | Reference | |
| Public | 294.2 | 1.01 (0.93, 1.09) | 330.0 | 1.00 (0.94, 1.08) | |
| Other | 312.8 | 1.07 (0.98, 1.16) | 372.8 | 1.11 (0.98, 1.24) | |
| Total Parenteral Nutrition | |||||
| Yes | 358.2 | 1.43 (1.30, 1.57)* | 394.5 | 1.32 (1.22, 1.43) | |
| No | 250.7 | Reference | 298.4 | Reference | |
| ICU level care | |||||
| Yes | 367.8 | 1.51 (1.39, 1.64)* | 389.8 | 1.29 (1.23, 1.36) | |
| No | 244.1 | Reference | 302.0 | Reference | |
aRate reported as number of days of use per 1000 inpatient days
*p-value <0.05
All models adjusted for presented covariates, chemotherapy course and diagnosis year.