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Effect of sildenafil administration on brain metabolic rate. A) Comparison of Cerebral metabolic rate of oxygen (CMRO2) between two time-points. CMRO2 increased after administration of sildenafil. B) The degree of CMRO2 change was significantly correlated with the individual’s baseline Montreal Cognitive Assessment (MoCA) scores (p = 0.04). The error bar is standard error of the mean.
