Table 1. Comparison of clinical features between iMCD and IgG4-RD.
iMCD (n=22) |
IgG4-RD (n=26) |
p-value | |
---|---|---|---|
Age | |||
Mean ± SD (years) | 53 ± 13 | 69 ± 10 | <0.001 |
<50 years (n, %) | 8 (36%) | 2 (8%) | 0.029 |
Gender (male %) | 45% | 73% | 0.077 |
Organ involvement | |||
Nodal | 5 (23%) | 0 | 0.015 |
Mixed nodal and extranodal | 14 (63%) | 14 (54%) | 0.565 |
Extranodal | 3 (14%) | 12 (46%) | 0.027 |
Affected organs (n, %) | |||
Lymph nodes | 19 (86%) | 14 (54%) | 0.027 |
Lungs | 15 (68%) | 18 (69%) | 1.000 |
Spleen (splenomegaly) | 7 (32%) | 0 | 0.002 |
Liver (hepatomegaly) | 3 (14%) | 0 | 0.089 |
Kidney | 2 (9%) | 8 (31%) | 0.085 |
Ureter/renal pelvis | 1 (5%) | 2 (8%) | 1.000 |
Retroperitoneum | 1 (5%) | 3 (12%) | 0.614 |
Paravertebral mass | 1 (5%) | 1 (4%) | 1.000 |
Prostate | 0 | 1 (4%) | 1.000 |
Pericardium | 0 | 2 (8%) | 0.493 |
Aorta (periaortitis) | 0 | 3 (12%) | 0.239 |
Bile duct | 0 | 5 (19%) | 0.054 |
Pancreas | 0 | 12 (46%) | <0.001 |
Salivary/lacrimal glands | 0 | 14 (54%) | <0.001 |
SD, standard deviation.