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| Time (hrs) | Rat plasma concentration (ng/mL) of ZB716 after a single oral dose | |||
|---|---|---|---|---|
| 1 mg/kg | 5 mg/kg | 10 mg/kg | 20 mg/kg | |
| 1 | 14.85±6.51 | 46.52±4.81 | 217.66±27.76 | 1044.53±153.17 |
| 3 | 9.23±2.33 | 23.37±2.80 | 93.58±21.77 | 670.93±125.16 |
| 6 | 4.70±1.66 | 15.92±2.03 | 62.04±14.86 | 370.93±111.46 |
| 8 | 4.42±2.38 | 11.42±0.52 | 60.74±13.93 | 299.84±118.47 |
| 24 | 1.36±1.42 | 9.37±1.24 | 33.09±10.58 | 98.53±36.11 |
