Table 2. Distribution of HLA-DP/DQ and STAT4 alleles in IgA nephropathy patients and healthy controls.

Genes	SNPs	Alleles	Controls (%)	IgAN (%)	Crude OR (95% CI)	P	Adjusted OR (95% CI)	p*
HLA-DP	rs3077	Allele G	658 (67.1)	157 (56.1)	1.00 (ref.)		1.00 (ref.)
		Allele A	322 (32.9)	123 (43.9)	1.60 (1.22–2.09)	0.001	1.69 (1.28–2.24)	2.2E-04
		HWE	p = 0.93	p =1.9E-15
HLA-DP	rs9277535	Allele G	610 (62.2)	128 (45.7)	1.00 (ref.)		1.00 (ref.)
		Allele A	370 (37.8)	152 (54.3)	1.96 (1.49–2.56)	1.0E-06	1.99 (1.52–2.63)	1.0E-06
		HWE	p = 0.99	p = 0.01
HLA-DQ	rs7453920	Allele G	855 (87.2)	251 (89.6)	1.00 (ref.)		1.00 (ref.)
		Allele A	125 (12.8)	29 (10.4)	0.79 (0.51–1.21)	0.28	0.70 (0.45–1.08)	0.11
		HWE	p = 0.26	p = 0.39
STAT4	rs7574865	Allele G	652 (66.5)	160 (57.1)	1.00 (ref.)		1.00 (ref.)
		Allele T	328 (33.5)	120 (42.9)	1.49 (1.14–1.96)	0.004	1.60 (1.21–2.12)	0.001
		HWE	p =0.82	p = 1.9E-08

OR: odds ratio; CI: confidence interval; HWE: Hardy-Weinberg equilibrium.

^*Logistic regression controlling for age and sex.

Bold values are statistically significant (p < 0.05).