Table 4. Summary of meta-analyses focused on CE-MRI and DWI for the assessment of breast cancer responses to NAC.
| Study | Search date | Comparative | No. | Technique | PSEN(95% CI) | PSPE(95% CI) | DOR(95% CI) | rDOR | AUC (95% CI) |
|---|---|---|---|---|---|---|---|---|---|
| Wu [30] | 2000 to 2012 | Indirect comparative | 30 | CE-MRI | 0.68 (0.57, 0.77) | 0.91 (0.87, 0.94) | 55.59 (21.80, 141.80) | NR | |
| 6 | DWI | 0.93 (0.82, 0.97) | 0.79 (0.74, 0.83) | 20.99 (13.24, 33.25) | 0.38 | NR | |||
| Liu [31] | 1992–2015 | Indirect comparative | 54 | CE-MRI | 0.68 (0.66, 0.78) | 0.84 (0.80, 0.88) | 13.82 (7.28,26.23) | 0.88 (NR) | |
| 8 | DWI | 0.79 (0.68, 0.88) | 0.75 (0.70, 0.80) | 18.68 (6.88–50.73 | 1.35 | 0.87 (NR) | |||
| Our | 2000 to 2017 | Direct comparative | 9 | CE-MRI | 0.84 (0.74, 0.91) | 0.76(0.64, 0.85) | 16.57 (9.80, 28.02) | 0.88(0.84, 0.90) | |
| 9 | DWI | 0.89 (0.81, 0.93) | 0.81(0.71, 0.89) | 33.72 (13.93, 81.59) | 2.04 | 0.91 (0.88, 0.93) |
Notes: No.= no. of studies; PSEN = pooled sensitivities; PSPE = pooled specificities; DOR = diagnostic odds ratio; AUC= areas under the ROC curve; DWI = diffusion weighted imaging; CE-MRI = contrast-enhanced MRI; rDOR = the ratio of DOR value of DWI divided by DOR value of CE-MRI; NR = not reported.