Table 5. Results of the association between Taq I polymorphism and PCa risk in different genotyping method.
| Comparison | Studies | Overall effect | Heterogeneity | Publication bias | ||||
|---|---|---|---|---|---|---|---|---|
| OR | Z-score | p-value | I2 | P-value | Begg's test | Egger's test | ||
| PCR-RFLP | ||||||||
| tt vs TT | 29 | 0.88 [0.71–1.01] | 1.13 | 0.258 | 46% | 0.006 | 0.393 | 0.283 |
| Tt vs TT | 29 | 0.94 [0.80–1.10] | 0.77 | 0.441 | 62% | 0.000 | 0.970 | 0.702 |
| tt/Tt vs TT | 29 | 0.91 [0.79–1.05] | 1.31 | 0.19 | 57% | 0.000 | 0.851 | 0.995 |
| tt vs TT/Tt | 29 | 0.90 [0.71–1.13] | 0.93 | 0.35 | 58% | 0.000 | 0.307 | 0.277 |
| t vs T | 29 | 0.92 [0.82–1.03] | 1.51 | 0.13 | 59% | 0.000 | 0.476 | 0.424 |
| TaqMan | ||||||||
| tt vs TT | 4 | 0.71 [0.53–0.94] | 2.38 | 0.017 | 32% | 0.219 | 1.000 | 0.794 |
| Tt vs TT | 4 | 0.85 [0.69–1.05] | 1.50 | 0.134 | 44% | 0.147 | 0.174 | 0.691 |
| tt/Tt vs TT | 4 | 0.82 [0.65–1.02] | 1.79 | 0.074 | 53% | 0.093 | 0.497 | 0.812 |
| tt vs TT/Tt | 4 | 0.77 [0.64–0.93] | 2.68 | 0.007 | 3% | 0.378 | 1.000 | 0.618 |
| t vs T | 4 | 0.83 [0.71–0.97] | 2.36 | 0.018 | 49% | 0.117 | 1.000 | 0.995 |
| SNPlex | ||||||||
| tt vs TT | 3 | 0.95 [0.75–1.20] | 0.43 | 0.669 | 0% | 0.322 | 0.317 | - |
| Tt vs TT | 3 | 0.91 [0.60–1.39] | 0.43 | 0.664 | 78% | 0.010 | 0.602 | 0.999 |
| tt/Tt vs TT | 3 | 0.92 [0.64–1.33] | 0.45 | 0.656 | 74% | 0.022 | 0.602 | 0.997 |
| tt vs TT/Tt | 3 | 1.01 [0.81–1.25] | 0.05 | 0.961 | 0% | 0.783 | 0.317 | - |
| t vs T | 3 | 0.96 [0.82–1.23] | 0.52 | 0.603 | 37% | 0.203 | 0.602 | 0.987 |