| IL-1β |
IL-1 |
Macrophages, monocytes |
Pro-inflammation, proliferation, apoptosis, differentiation |
| IL-4 |
IL-4 |
Th-cells |
Anti-inflammation, T-cell and B-cell proliferation, B-cell differentiation |
| IL-6 |
IL-6 |
Macrophages, T-cells, adipocyte |
Pro-inflammation, differentiation, cytokine production |
| IL-8 |
CXC |
Macrophages, epithelial cells, endothelial cells |
Pro-inflammation, chemotaxis, angiogenesis |
| IL-10 |
IL-10 |
Monocytes, T-cells, B-cells |
Anti-inflammation, inhibition of the pro-inflammatory cytokines |
| IL-12 |
IL-12 |
Dendritic cells, macrophages, neutrophils |
Pro-inflammation, cell differentiation, activates NK cell |
| IL-11 |
IL-6 |
Fibroblasts, neurons, epithelial cells |
Anti-inflammation, differentiation, induces acute phase protein |
| TNF-α |
TNF |
Macrophages, NK cells, CD4+lymphocytes, adipocyte |
Pro-inflammation, cytokine production, cell proliferation, apoptosis, anti-infection |
| IFN-γ |
INF |
T-cells, NK cells, NKT cells |
Pro-inflammation, innate, adaptive immunity anti-viral |
| GM-CSF |
IL-4 |
T-cells, macrophages, fibroblasts |
Pro-inflammation, macrophage activation, increase neutrophil and monocyte function |
| TGF-β |
TGF |
Macrophages, T cells |
Anti-inflammation, inhibition of pro-inflammatory cytokine production |
