Table 1.
Patient Characteristics
| N=91 | % | ||
|---|---|---|---|
| Sex | Male | 41 | 45.05 |
| Female | 50 | 54.95 | |
|
| |||
| Pathology | Non-Small Cell Lung Cancer | 39 | 42.86 |
| Melanoma | 17 | 18.68 | |
| Breast Cancer | 11 | 12.09 | |
| Renal Cell Carcinoma | 8 | 8.79 | |
| Colon Cancer | 3 | 3.3 | |
| Other | 10 | 10.99 | |
| Unknown | 3 | 3.3 | |
|
| |||
| Number of Intracranial Metastases | Median (Min, Max) | 1 | (1, 19) |
| Number Category | Single | 64 | 70.33 |
| > 1 | 27 | 29.67 | |
|
| |||
| Diameter of Index Metastasis (cm) | Median (Min, Max) | 3.6 | (1.4, 7.3) |
| Diameter Category | > 3 cm | 61 | 67.03 |
| ≤ 3 cm | 30 | 32.97 | |
|
| |||
| Tumor Location | Supratentorial | 62 | 68.13 |
| Infratentorial | 29 | 31.87 | |
|
| |||
| Time from Surgery to Radiosurgery* | > 30 days | 52 | 57.78 |
| ≤ 30days | 38 | 42.22 | |
|
| |||
| Type of Radiosurgery* | Gamma Knife | 58 | 64.44 |
| LINAC | 32 | 35.56 | |
|
| |||
| Dose Schedule* | Single Fraction | 65 | 72.22 |
| > 1 Fraction | 25 | 27.78 | |
|
| |||
| Surgical Result | Gross Total Resection | 70 | 76.92 |
| Subtotal Resection | 21 | 23.08 | |
|
| |||
| Local Failure | Yes | 20 | 21.98 |
| No | 71 | 78.02 | |
| 12-Month Survival Rate | 76 | 83.52 | |
|
| |||
| LMD Failure | Yes | 32 | 35.16 |
| No | 59 | 64.84 | |
| 12-Month Survival Rate | 63 | 69.23 | |
*
a single patient suffered LMD after resection and before radiosurgery; patient treated with WBRT
LMD – leptomeningeal disease; LINAC – linear accelerator