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. 2018 Feb 8;8:2624. doi: 10.1038/s41598-018-21084-8

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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In vitro studies. (A) Shows the drug dose-response plots for MDA-MB-231, MCF-7, and B16F10 cells. (B) Shows stacked histogram for the percentage of the cellular population in different apoptotic phases after treatment with the respective formulation. (C) Hydrodynamic diameter of the PSPL and PSPLBC, pre- and post-incubation with FBS for 02 hours. (D) Shows the levels of secreted TNF-α, IFN-γ and IL-6 cytokines by the PSPLBC treated RAW cells (*p ≤ 0.05, ns = not significant).