Fig. 8.

Close apposition and interactions of the Kv11.1 N-tail with the S4–S5, S2–S3 and C-linkers of the channel. a Lateral view of the Kv11.1 tetrameric structure ([60] PDB code 5VA2). A highlighted subunit is coloured in gray. b Enhanced view of the region inside the signalled square in a with ribbons corresponding to the indicated domains and residue symbols coloured as shown at the bottom. Lateral chains of the selected residues are shown as ball and stick with oxygen and nitrogen atoms as red and blue spheres. Dashed lines indicate interatomic distances ranging between 3.0 and 5.4 Å. Structures were processed with UCSF Chimera [39]