Table III.

Characteristics of six studies evaluating procalcitonin (PCT) for the diagnosis of periprosthetic joint infection (PJI)

Study	No. of patients	Study design	Cutoff	Joint	Reference test
Yuan et al,67 2015	75	Prospective	0.5 ng/ml	Hip	Histology, intraoperative findings
Ettinger et al,30 2015	77	Prospective	0.025 ng/ml	Hip, knee, shoulder	Histology, microbiology, intraoperative findings
Randau et al,32 2014	120	Prospective	46 ng/ml	Hip, knee	Histology, microbiology, intraoperative findings
Glehr et al,29 2013	124	Prospective	0.35 ng/ml; 0.055 ng/ml	Hip, knee	Histology, microbiology, intraoperative findings
Worthington et al,39 2010	46	Prospective	0.5 ng/ml	Hip	Microbiology
Bottner et al,27 2007	78	Prospective	0.3 ng/ml	Hip, knee	Histology, intraoperative findings

Reproduced with permission from: Xie K, Qu X, Yan M. Procalcitonin and alpha-Defensin for Diagnosis of Periprosthetic Joint Infections. J Arthroplasty 2017;32:1387-1394. The reference numbers given in the ‘Study’ column correspond with the reference list in this paper, not the reference list given by Xie et al in their original study