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. 2018 Jan 31;15(138):20170804. doi: 10.1098/rsif.2017.0804

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© 2018 The Author(s).

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 3. — Schematic diagrams of the derived piecewise deterministic Markov process (PDMP) for (a) idealized activator-titration circuit (ATC) and (b) idealized repressor-titration circuit (RTC). Both models have a single promoter site . The linearized PDMP for ATC and RTC are shown in (c) and (d), respectively, where the green circular arrows indicates the direction of the emergent stochastic cycles. Dark blue and light red boxes denote promoter states with different production rates where and , respectively. The transitions between the two regimes and () are due to titration. (Online version in colour.)

Inline graphic — Schematic diagrams of the derived piecewise deterministic Markov process (PDMP) for (a) idealized activator-titration circuit (ATC) and (b) idealized repressor-titration circuit (RTC). Both models have a single promoter site . The linearized PDMP for ATC and RTC are shown in (c) and (d), respectively, where the green circular arrows indicates the direction of the emergent stochastic cycles. Dark blue and light red boxes denote promoter states with different production rates where and , respectively. The transitions between the two regimes and () are due to titration. (Online version in colour.)