Skip to main content
. 2018 Jan 31;15(138):20170804. doi: 10.1098/rsif.2017.0804

Table 1.

Descriptions and values of the idealized model parameters.

parameter description ATC RTC order of reaction
Ω characteristic system size 103 103 n.a.
λ scaling factor of the binding rate κZ and unbinding rate θZ, Z ∈ {X, Y} (1, 103) (1, 103) n.a.
Inline graphic number of binding sites on gene X 0 (1, 3) n.a.
Inline graphic number of binding sites on gene Y (1, 3) 0 n.a.
βfX basal production rate of gene X when the number of bound Inline graphic 2 10 zeroth order
βbX repressed production rate of gene X when the number of bound Inline graphic 2 0 zeroth order
βfY basal production rate of gene Y when the number of bound X = 0 0 2 zeroth order
βbY activated production rate of gene Y when the number of bound X > 0 10 2 zeroth order
δX degradation rate of TF X 1 1 first order
δY degradation rate of inhibitor Y 1 1 first order
κX the binding rate of TF X to an empty target promoter site on gene X 0 0.2λ second order
κY the binding rate of TF X to an empty target promoter site on gene Y λ 0 second order
θX the dissociation rate of a TF X bound to promoter sites of X 0 0.4λ first order
θY the dissociation rate of a TF X bound to promoter sites of Y 0.5λ 0 first order
α the association rate of X and Y 10 10 second order