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. 2018 Jan 22;7(2):454–462. doi: 10.1002/cam4.1296

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© 2018 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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KHDRBS3‐modulated CD44 isoform enhances stemness. (A) An agarose gel electrophoresis image of CD44 variant expression is shown. Arrow indicates the isoform on which we focused in this study (CD44v). The structure of CD44v is depicted. (B) CD44v‐overexpressing cells were established. Immunoblotting images are shown. (C) Spheres of the control and KHDRBS3 knockdown cells are shown. ShKHDRBS3 #1 was used. Arrowheads indicate spheres larger than 50 μm. (D) Numbers of spheres are graphed. Scale bar: 100 μm. *P < 0.05, **P < 0.01.