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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Lung Cancer. 2018 Jan 4;116:90–95. doi: 10.1016/j.lungcan.2018.01.002

Table 1. Baseline Clinical, Pathologic, and Biomarker Testing Characteristics of Lung Adenocarcinomas from 2004-2017.

Age at time of tissue acquisition Median years-old (range) 66 (27-92)
Gender
 Women n (%) 594 (58.9%)
 Men n (%) 415 (41.1%)
Race n (%)
 White 789 (78.2%)
 Asian 108 (10.7%)
 Black 74 (7.3%)
 Other/Multiple 38 (3.7%)
Ethnicity n (%)
 Non-Hispanic 980 (97.1%)
 Hispanic 29 (2.9%)
Smoking status n (%)
 Current smoker 240 (23.8%)
 Former smoker 529 (52.5%)
 Never smoker 238 (23.6%)
Pack-years smoking
Median (range) 30 (0-240)
Stage at tumor analyses n (%)
 I 47 (4.7%)
 II 67 (6.7%)
 III 145 (14.4%)
 recurrent 61 (6.1%)
 IV 687 (68.2%)
Histology n (%)
 Adenocarcinoma 899 (89.1%)
 NSCLC (NOS) 55 (5.5%)
 Squamous cell carcinoma 38 (3.8%)
 Other 17 (1.7%)
Type of tissue n (%)
 Surgical specimen 359 (35.6%)
 Small biopsy 264 (26.2%)
 Cytology block from aspirate/fluid 385 (38.2%)
Anatomic site of tissue acquisition n (%)
 Lung 445 (44.1%)
 Mediastinal/hilar lymph node 224 (22.2%)
 Pleura 132 (13.1%)
 Soft tissue/bone 57 (5.6%)
 Brain 53 (5.3%)
 Liver 31 (3.1%)
 Extra-thoracic lymph node 29 (2.9%)
 Adrenal 8 (0.8%)
 Other 30 (3.0%)
Tumor biomarker testing n (%, from total cases)
EGFR mutation (exons 18-21) 1009 (100%)
ALK rearrangement (FISH, IHC or NGS) 895 (88.7%)
ROS1 rearrangement (FISH, IHC or NGS) 537 (53.2%)
KRAS mutation 841 (83.3%)
BRAF mutation 143 (14.2%)
ERBB2 mutation 144 (14.3%)
 NGS-based testing/other technology 179 (17.7%)