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Relationship between degree of FXR expression according to colonic location and disease type
| Location of samples | Study group | Absent-weak FXR expression, n (%) | Moderate-strong FXR expression, n (%) | p value |
|---|---|---|---|---|
| TI | HC | 1 (9.1) | 10 (90.9) | 0.59 |
| MC | 3 (23.1) | 10 (76.9) | ||
| RC | HC | 10 (35.7) | 18 (64.3) | <0.001 |
| MC | 30 (78.9) | 8 (21.1) | ||
| LC | HC | 19 (38.7) | 12 (38.7) | 0.001 |
| MC | 44 (91.7) | 4 (8.3) |
FXR, farnesoid X receptor; TI, terminal ileum; RC, right colon; LC, left colon; HC, healthy controls; MC, microscopic colitis.
