FIG 1 .

Diagram of the P. aeruginosa PAO1 carnitine catabolism operon and the catabolic pathway. (A) Arrows represent the individual open reading frames of the carnitine catabolism operon and the regulator chdR. Below the arrow is the designated gene name. (B) Diagram of the cdhR-caiX intragenic region organized such that caiX transcription occurs left to right. The orange box denotes the cdhR 5′ UTR, the dark green box marks the position of the CdhR and GbdR binding sites (CdhR binding sequence listed below), and the light green box denotes the caiX 5′ UTR. (C) Diagram of the converging carnitine and choline catabolism pathways. Black arrows represent an enzymatic step in the catabolic pathway, and the gene names are italicized below. The blue arrows represent positive regulation by either CdhR or GbdR, and the T-bar represents repression by BetI.