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Homology models of epitope F interactions between days 262 and 581 viruses. (A) Amino acid positions 327, 401, and 404 are shown in green on the P2 dimer for context. (B and C) Three hydrogen bonds (red dashed lines) are evident among residues 327V, 401Q, and 404V in the day 262 model (B), while the original three hydrogen bonds (red dashed lines) plus two additional hydrogen bonds (blue dashed lines) are formed in the day 581 model (C) among 327K, 401Q, and 404E.
