Table V.
Stem cell markera | SUL-S | SUL-R | δ-SUL-S |
---|---|---|---|
Tumor spheroids | 2.3±1.7 | 18.7±3.3 | +7.1Xb |
CD44 (FU) | 2.1±0.6 | 14.4±1.5 | +5.7Xc |
CD133 (FU) | 3.1±1.2 | 14.2±1.3 | +3.6Xd |
c-Myc (FU) | 2.6±0.7 | 7.0±0.5 | +1.7Xe |
Mean ± standard deviation (n=3 per treatment group).
P=0.01 compared with the SUL-S phenotype.
P=0.02 compared with the SUL-S phenotype. Data were analyzed by Student's t-test. SUL-S, sulindac-sensitive; SUL-R, sulindac-resistant; FU, log mean fluorescence units; Apc, adenomatous polyposis coli; X, fold-change.