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. 2018 Feb 8;19:47. doi: 10.1186/s12859-018-2040-6

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© The Author(s) 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Data Analysis. a The phenotype distribution based on the genes it associates with. b The distribution of newly added phenotypes based on whether they have known disease causing gene(s). c The AUC20 scores of different methods in two situations: 1. phenotypes with known disease genes are used as queries (left); 2. phenotypes with unknown disease genes are used as queries (right)