Table 1.
Clinical characteristics of the participants to the population-based Australian Breast Cancer Family Registry that were genotyped for RNASEL:p.Glu265*
| Cases (n = 1445) | Controls (n = 827) | |
|---|---|---|
| Age at diagnosis (years) | 42 [23–59] | n/a |
| Age at recruitment (years) | 43 [23–60] | 41 [20–60] |
| Ethnicity | ||
| White/Caucasian | 1345 (93%) | 710 (85.9%) |
| Asian and Pacific Islander | 85 (5.9%) | 32 (3.9%) |
| Other | 8 (0.6%) | 7 (0.8%) |
| Unknown | 7 (0.5%) | 78 (9.4%) |
| Laterality | ||
| Right breast | 713 (49.3%) | n/a |
| Left breast | 732 (50.7%) | n/a |
| Estrogen Receptor Status | ||
| Negative | 439 (30.4%) | n/a |
| Positive | 815 (56.4%) | n/a |
| Unknown | 191 (13.2%) | n/a |
| Grade | ||
| GI | 212 (14.6%) | n/a |
| GII | 526 (36.4%) | n/a |
| GIII | 555 (38.4%) | n/a |
| GIV | 3 (0.2%) | n/a |
| Unknown | 149 (10.4%) | n/a |
n/a: not applicable
GI, grade I; GII, grade II; GIII, Grade III; GIV, Grade IV