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. 2018 Jan 22;62(1):2847. doi: 10.4081/ejh.2018.2847

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©Copyright K. Hashimoto et al., 2018

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

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Figure 3. — The panels show representative articular cartilage staining with SFO (A-F). Articular cartilage of WT mice at day 1, 3, and 7 after zymosan injection (A-C). Articular cartilage of LOX-1 KO mice at day 1, 3, and 7 after zymosan injection (D-F). All specimens are in the sagittal direction. The graphs show the score of cartilage degeneration in the zymosan-injected knees (G), and saline-injected knees (H) at each experimental time. Cartilage degeneration was lesser in the cartilage of LOX-1 KO mice (D-F) than in WT mice (A-C) during all experimental times. Data are presented as mean ± SD (n= 10, in each group); P<0.05 was regarded as a significant difference (Student’s ttest). N.S, not significant. Scale bars: 100 μm.