Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan 22;62(1):2847. doi: 10.4081/ejh.2018.2847

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

©Copyright K. Hashimoto et al., 2018

This article is distributed under the terms of the Creative Commons Attribution Noncommercial License (by-nc 4.0) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.

PMC Copyright notice

Figure 6. — The panels show representative tibial cartilage immunostaining of LOX-1 and ox-LDL (A-L) at 400× magnification. LOX-1 expression in the cartilage of WT mice at day 1, 3 and 7 after zymosan injection (A-C). Ox-LDL expression in the cartilage of WT mice at day 1, 3 and 7 after zymosan injection (D-F). LOX-1 expression in the cartilage of LOX-1 KO mice at day 1, 3 and 7 after zymosan injection (G-I). Ox-LDL expression in the cartilage of LOX-1 KO mice at day 1, 3 and 7 after zymosan injection (J-L). Although LOX-1 and ox- LDL positive cells are observed in WT mice (A-F), no positive cells are observed in LOX-1 KO mice (G-L) during all the experimental time. The graphs show the correlation between the positive cell rate for LOX-1 (M), ox-LDL (N) and the cartilage degeneration score in WT mice. The positive correlation is observed between positive cell rate for LOX-1 or ox-LDL in chondrocytes and the cartilage degeneration score. Arrows show the LOX-1 or ox-LDL positive chondrocytes. The antibodies used were rabbit anti-mouse LOX-1 polyclonal antibody and rabbit anti-mouse ox-LDL polyclonal antibody. Scale bars: 100 μm.