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. 2018 Jan 22;62(1):2847. doi: 10.4081/ejh.2018.2847

Figure 7.

Figure 7.

The panels show representative synovial tissues with immunostaining of MMP-3 (A-F). MMP-3 expression in the synovial cells of WT mice at day 1, 3 and 7 after zymosan injection (A-C) at 200× magnification. MMP-3 expression in the synovial cells of LOX-1 KO mice at day 1, 3 and 7 after zymosan injection (D-F). MMP-3 positive cells are observed both in synovial cells of WT (A-C) and LOX-1 KO mice (D-F) during all the experience time. At day 7, MMP-3 in synovium of LOX-1 KO mice (F) is stained weaker than in that of WT mice (C). The graphs show the positive cell score of MMP-3 expression in the synovium of WT and LOX-1 KO mice after zymosan injection at each experimental time (G). The antibodies used were rabbit anti-mouse MMP-3 polyclonal antibody. Data are presented as mean ± SD (n= 10, in each group); P<0.05 was regarded as a significant difference (Student’s t-test). N.S, not significant. Scale bars: 100 μm.