TABLE 4.

Initial Treatment Characteristics by Race and County

2000—2006													2007–2012
	Edgecombe			Nash			Orange			AA, E vs O	AA, E vs N	AA, N vs O	Edgecombe			Nash			Orange			AA, E vs O	AA, E vs N	AA, N vs O
	AA	CA	p	AA	CA	p	AA	CA	p	p-value			AA	CA	p	AA	CA	p	AA	CA	p	p-value
Number of cases	158	142		158	347		79	495					140	115		148	280		73	506
Patients with Localized Disease
Diagnosis to 1st Treatment, Days (SD)	23.0 (3.5)	17.4 (2.3)	.186	24.6 (3.3)	14.8 (24.6)	.007	25.1 (3.1)	19.8 (1.0)	.081	.704	.738	.920	21.3 (2.2)	21.5 (2.3)	.945	22.9 (2.8)	20.5 (1.7)	.444	26.6 (2.4)	23.5 (1.0)	240	.116	.649	.359
Surgery [n, (%)]
Yes	95 (100.0)	94 (~98)	.101	94 (100.0)	231 (100.0)	.180	42 (~98)	305 (~98)	.339	.105	.313	.101	69 (~97)	66 (~96)	.740	78 (~99)	184 (~99)	.609	48 (~94)	335 (~97)	280	.701	.623	.959
No/Unknown	0 (0.0)	<11 (~2)		0 (0.0)	0 (0.0)		<11 (~2)	<11 (~2)					<11 (~3)	<11 (~4)		<11 (~1)	<11 (~1)		<11 (~6)	<11 (~6)
Type of Surgery [N, (%)]
BCS	71 (74.7)	68 (72.3)	.897	68 (72.3)	163 (70.6)	.955	24 (57.1)	198 (64.9)	.454	.087	.800	.133	50 (72.4)	44 (66.7)	.438	55 (70.5)	125 (67.9)	.529	30 (62.5)	207 (61.8)	924	.117	.701	.176
Mastectomy	24 (25.3)	26 (27.7)		26 (27.7)	68 (29.4)		18 (42.9)	107 (35.1)					19 (27.5)	22 (33.3)		23 (29.5)	59 (32.1)		18 (37.5)	128 (38.2)
BCS+/−Radiation Therapy [N, (%)]
BCS plus RT	47 (67.1)	54 (79.4)	.104	53 (80.3)	132 (82.5)	.697	17 (~71)	140 (72.5)	.860	.738	.082	.339	43 (~85)	34 (~75)	.273	48 (~90)	105 (85.4)	.348	22 (~73)	159 (79.9)	410	.160	.470	.039
BCS no RT	23 (32.9)	14 (20.6)		13 (19.7)	28 (17.5)		<11 (~30)	53 (27.5)					<11 (~15)	<11 (~25)		<11 (~10)	18 (14.6)		<11 (~27)	40 (20.1)
Patients with Regional Disease
Diagnosis to 1st Treatment, Days (SD)	23.5 (27.1)	21.1 (23.1)	.654	19.9 (20.6)	15.8 (19.0)	.224	25.5 (324)	19.9 (19.3)	.205	.764	.438	.336	25.5 (24.2)	19.9 (19.1)	.238	19.2 (19.6)	19.7 (17.4)	.879	32.4 (45.5)	21.8 (16.4)	041	.388	.136	.076
Surgery [N, (%)]
Yes	51 (98.1)	40 (100.0)	.378	50 (92.6)	92 (94.9)	.895	25 (89.3)	145 (91.2)	.746	.085	.317	.409	56 (~97)	35 (~95)	.643	49 (~88)	78 (~98)	.006	17 (~90)	136 (91.9)	.642	.228	.073	.819
No / Unclear	<11 (~2)	0 (0.0)		<11 (~7)	<11 (~5)		<11 (~10)	14(8.8)					<11(~3)	<11 (~5)		<11 (~12)	<11 (~2)		<11 (~10)	12 (8.1)
Type of Surgery [N, (%)]
BCS	23 (44.2)	14 (35.0)	.330	29 (56.9)	38 (39.6)	.047	<11 (~25)	64 (43.5)	.059	.075	.195	.005	34 (59.7)	14 (37.8)	.049	30 (57.7)	32 (40.5)	.057	<11 (~30)	53 (38.4)	.444	.075	.957	.074
Mastectomy	29 (55.8)	26 (65.0)		22 (43.1)	58 (60.4)		19 (~75)	83 (56.5)					23 (40.4)	23 (62.2)		22 (42.3)	47 (59.5)		12 (~70)	85 (61.6)
Surgery +/− Radiation [N, (%)]
Surgery plus RT	23 (44.2)	19 (47.5)	.755	27 (50.0)	41 (42.3)	.360	12 (42.9)	71 (44.7)	.860	.906	.552	.539	41 (70.7)	21 (56.8)	.164	37 (66.1)	43 (54.4)	.175	<11 (~54)	90 (60.8)	.493	.149	.596	.295
Surgery no/unclear RT	29 (55.8)	21 (52.5)		27 (50.0)	56 (57.7)		16 (57.1)	88 (55.4)					17 (29.3)	16 (43.2)		19 (33.9)	36 (45.6)		<11 (~46)	58 (39.2)
Chemotherapy
Yes	38 (73.1)	25 (62.5)	.232	40 (74.1)	63 (65.0)	.377	18 (~64)	119 (74.8)	.374	.142	.864	.181	46 (79.3)	22 (59.5)	.025	47 (~84)	52 (65.8)	.025	16 (~84)	110 (74.3)	.728	.837	.478	.758
No / Unknown	14 (26.9)	15 (37.5)		14 (25.9)	34 (35.1)		<11 (~36)	40 (25.2)		12 (20.7)	15 (40.5)					<11 ('16)	27 (34.2)		<11 ('16)	38 (25.7)
Patients with Distant Disease
Analysis not feasible due to small sample size

Note. AA, African Americans; BCS, Breast Conserving Surgery; CA, Caucasian Americans; E vs N, Edgecombe County vs Nash County; E vs O, Edgecombe County vs Orange County; N vs O, Nash County vs Orange County; RT, radiation therapy; SD, standard deviation.

+ Two-sided T-test for continuous variables; Chi-square test for categorical variables, which exclude “unknown” category.

In some instances (eg, <11, (~5)) actual values are suppressed due to small sample size, per data use agreement requirements.