Figure 3.

Changes in brain oxygen metabolism across sleep–wake stages were associated with neurodevelopmental outcome. Cerebral rSO₂ cycled across sleep–wake stages for a full term newborn with HIE who had normal Bayley Scales of Infant Development, 3rd edition, scores across all domains at 18 months (A). The changes across sleep–wake stages was muted for another term newborn with HIE who had quadriparetic cerebral palsy, no expressive language, and treatment-resistant epilepsy when she died at age 15 months (B).