Table 1.
Clinical and Demographic Profile of 50 Newborns who Underwent Polysomnography.
| Variable | N = 50 with PSG | N = 40 with any outcome data | N = 29 with Bayley-III |
|---|---|---|---|
| Sex | 29 males | 24 males | 17 males |
| Gestational age | 39.2 ± 1.7 weeks | 39.3 ± 1.5 weeks | 39.6 ± 1.4 weeks |
| Birth weight | 3361 ± 565 g | 3339 ± 575 g | 3419 ± 531 g |
| Head circumference | 34.5 ± 1.9 cm | 34.7 ± 2.0 cm | 34.7 ± 1.7 cm |
| 5-minute Apgar score | Median 8 [IQR 5, 10] | Median 8 [IQR 4, 10] | Median 8.5 [IQR 4.75, 10] |
| Thompson score | Median 4 [IQR 2, 9] | Median 4.5 [IQR 2, 10] | Median 4 [IQR 2, 9] |
| SNAPPE-II score | Median 24 [IQR 15, 45.5] | Median 26 [IQR 19, 49] | Median 26 [19, 49] |
| Primary neurologic diagnosis | HIE N = 15 Seizures (without obvious cause) N = 5 Epilepsy N = 5 (three epileptic encephalopathies, two benign neonatal seizures) Infection N = 5 Apnea N = 7 Arterial ischemic stroke N = 3 Other N = 9 |
HIE N = 14 Seizures (without obvious cause) N = 5 Epilepsy N = 3 (two epileptic encephalopathies; 1 benign neonatal seizure) Infection N = 3 Apnea N = 7 Stroke N = 2 Other N = 4 |
HIE N = 11 Seizures (without obvious cause) N = 5 Epilepsy N = 2 (one epileptic encephalopathy, 1 benign neonatal seizure) Apnea N = 4 Other N = 4 |
| Therapeutic hypothermia | 11 | 10 | 8 |
| Received phenobarbitala | 24 | 22 | 17 |
| Bayley-III cognitive score (N = 28) | 97 ± 19 | ||
| BAYLEY-III language score (N = 27) | 88 ± 21 | ||
| Bayley-III motor score (N = 26) | 90 ± 18 |
PSG = polysomnogram; HIE = hypoxic ischemic encephalopathy; Bayley-III = Bayley Scales of Infant Development, 3rd edition.
aFour patients received levetiracetam in addition to phenobarbital; of these, two also received fosphenytoin and one was treated with a lidocaine infusion.