Table 1.

Primary breast tumor (PBT) and sentinel lymph node (SLN) metastasis analyzed by FISH and IHC for BP1 and HER2/NEU gene copy number and protein expression, respectively

PATIENT#	TISSUE	FISH BP1	IHC BP1	FISH HER2/NEU	IHC HER2/NEU
1	PBT	Normal	pos	Gain	pos
2	PBT	Gain	pos	Amplification	pos
3	PBT	Amplification	pos	Amplification	pos
4	PBT	Normal	pos	Normal	neg
5	PBT	Normal	pos	Amplification	pos
6	PBT	Normal	neg	Gain	neg
7	PBT	Normal	pos	Normal	neg
8	PBT	Normal	neg	Amplification	neg
9	PBT	Normal	pos	Amplification	neg
10	PBT	Normal	pos	Normal	pos
11	SLN	Normal	pos	–	–
12	SLN	Gain	–	–	–
13	PBT	Amplification	pos	Gain	neg
	SLN	Normal	pos	–	–
14	PBT	Amplification	pos	Amplification	neg
	SLN	Gain	pos	Gain	neg
15	PBT	Gain	pos	Normal	neg
	SLN	Normal	pos	Normal	neg
16	PBT	Normal	pos	Normal	neg
	SLN	Normal	pos	–	–
17	PBT	Amplification	pos	Amplification	pos
	SLN	Normal	pos	Normal	neg
18	PBT	Normal	neg	Normal	neg
	SLN	Normal	pos	Normal	neg
19	PBT	Normal	pos	Normal	neg
	SLN	Normal	pos	Normal	neg
20	PBT	Gain	–	Gain	pos
	SLN	Gain	pos	Gain	neg
21	PBT	Normal	pos	Normal	neg
	SLN	Normal	pos	Normal	neg
22	PBT	Amplification	–	Normal	neg
	SLN	Amplification	–	Normal	neg
23	PBT	Normal	pos	Normal	neg
	SLN	Normal	pos	Normal	neg
24	PBT	Normal	pos	Normal	neg
	SLN	Normal	pos	Normal	neg

Abbreviations: pos, positive; neg, negative; –, result not obtained.