Table 2.
Geometric mean HI titers and vaccine group ratios at 21 days after last vaccination in the overall population (children aged 6 to <72 months).
| Vaccine group | aTIV (n = 114) | TIV (n = 112) | aTIV:TIV | |
|---|---|---|---|---|
| A(H1N1) | Day 1 (95% CI) | 14 (11–19)* | 15 (11–20) | |
| Day 21 (95% CI) | 675 (536–849) | 166 (132–208) | 4.06 (3.00–5.51) | |
| A(H3N2) | Day 1 (95% CI) | 59 (40–86) | 55 (38–81) | |
| Day 21 (95% CI) | 1280 (1077–1521) | 495 (417–588) | 2.58 (2.05–3.25) | |
| B | Day 1 (95% CI) | 7.47 (6.41–8.71) | 6.92 (5.95–8.06) | |
| Day 21 (95% CI) | 76 (61–93) | 16 (13–20) | 4.67 (3.52–6.20) | |
*
n = 113
Bold data points indicate non-inferiority criterion was met based on the lower limit of the 2-sided 95% CI of the vaccine group ratios being above 0.67 for each strain.
aTIV, adjuvanted trivalent influenza vaccine; CI, confidence interval; HI, hemagglutination inhibition; TIV, trivalent influenza vaccine.