Table 3.
Geometric mean titers and ratios at 21 days after last vaccination, by age group.
| Vaccine group ratios |
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Age groups | 6 – <18 months |
18 – <36 months |
36 – <72 months |
6 – <18 months | 18 – <36 months | 36 – <72 months | ||||
| Vaccine group | aTIV (n = 34) | TIV (n = 32) | aTIV (n = 37) | TIV (n = 38) | aTIV (n = 43) | TIV (n = 42) | aTIV:TIV | aTIV:TIV | aTIV:TIV | |
| A(H1N1) | Day 21 (95% CI) | 480 (282–815) | 40 (24–68) | 850 (596–1213) | 196 (139–276) | 718 (452–1141) | 410 (251–670) | 12 (6.63–22) | 4.34 (2.73–6.91) | 1.75 (1.09–2.83) |
| Day 21:Day 1 (95% CI) | 90 (53–154) | 6.71 (3.92–11) | 54 (33–90) | 15 (9.05–24) | 22*(11–43) | 11 (5.44–23) | 13 (7.5–24) | 3.67 (1.9–7.07) | 1.97 (0.98–3.97) | |
| A(H3N2) | Day 21 (95% CI) | 1006 (632–1601) | 151 (95–242) | 1465 (1157–1855) | 609 (485–766) | 1547 (1144–2092) | 1171 (850–1613) | 6.65 (4.00–11) | 2.40 (1.77–3.27) | 1.32 (0.97–1.80) |
| Day 21:Day 1 (95% CI) | 93 (46–188) | 15 (7.3–30) | 22 (13–37) | 10 (6.27–17) | 8.22 (4.84–14) | 6.10 (3.47–11) | 6.28 (2.90–14) | 2.14 (1.09–4.21) | 1.35 (0.78–2.33) | |
| B | Day 21 (95% CI) | 75 (50–112) | 8.43 (5.64–13) | 95 (65–139) | 21 (15–30) | 90 (56–145) | 31 (19–52) | 8.89 (5.73–14) | 4.51 (2.76–7.36) | 2.89 (1.77–4.73) |
| Day 21:Day 1 (95% CI) | 14 (9.44–21) | 1.56 (1.05–2.33) | 11 (7.27–18) | 2.67 (1.74–4.09) | 11 (6.79–18) | 3.94 (2.34–6.63) | 9.00 (5.81–14) | 4.23 (2.38–7.52) | 2.81 (1.70–4.64) | |
*
n = 42
aTIV, adjuvanted trivalent influenza vaccine; CI, confidence interval; TIV, trivalent influenza vaccine.