Table 1.
Study | Year | Design | Participants | Administrating method | Dosing groups |
---|---|---|---|---|---|
Creech17 | 2017 | Prospective,multicentre,randomized, controlled, double-blind | Participants receiving SA3Ag or SA4Ag or placebo | a single 0.5 mL intramuscular injection into the deltoid muscle | SA3Ag, low-dose SA4Ag, mid-dose SA4Ag, high-dose SA4Ag, placebo |
Frenck16 | 2017 | Prospective,multicentre,randomized, controlled, double-blind | Participants receiving SA4Ag or placebo | a single 0.5 mL intramuscular injection into the deltoid muscle | Low-dose SA4Ag, mid-dose SA4Ag, high-dose SA4Ag, placebo |
Nissen20 | 2015 | Prospective,multicentre,randomized, controlled, double-blind | Participants in the two age groups receiving SA3Ag or placebo, independently | Not Reported | Low-dose SA3Ag, mid-dose SA3Ag, high-dose SA3Ag, placebo |
SA3Ag: Staphylococcus aureus three-antigen vaccine; SA4Ag: Staphylococcus aureus four-antigen vaccine.