Figure 7.

Influence of SY on LPS-induced inflammatory factors and NO release by BV2 microglia. BV2 microglia were treated with LPS (0.5 μg/mL) or LPS (0.5 μg/mL) plus SY (80 μg/mL) for 48 h. The levels of IL-1β, IL-6, TNF-α, and IL-10 in culture supernatants were measured by ELISA assay (a–d), COX-2 expression was determined by western blot assay (e), and NO generation was evaluated by the Griess reaction (f). Quantitative results are expressed as mean ± SEM from three independent experiments with similar results (in triplicate/each experiment). *P <0.05, **P <0.01, ***P <0.001.