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. 2016 Jul 9;29(3):426–437. doi: 10.1177/0394632015621319

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Figure 4. — The representative hepatic histopathology: (a, b) Control and blueberry (BB) groups: Normal histologic appearance of liver (H&E ×200); (c, d) DEN group: Lobular architecture, parenchymal nodules, distinct fibrosis in portal-portal and portal-central areas, inflammatory cells, necrotic parenchymal cells, indicating incomplete cirrhosis (H&E ×100 and ×200; respectively); (e) DEN + BB group: Portal-central and portal-portal fibrosis as thin fibrous septa (H&E ×200). According to Ishak stages, fibrosis scores were significantly (P <0.05) decreased in the DEN + BB group (2.66 ± 0.81) as compared to the DEN group (4.00 ± 1.09). The Gomori Reticulin stain exposed the reticulin fibers of fibrotic areas clearly in DEN (f) and DEN + BB (g) groups (×200). However, DEN + BB group showed weaker reticulin frame work than DEN group.