Table 2. Downregulated genes in dorsal and ventral retina following a PT injury.
Fold changes comparing injured retina to region matched normal controls.
| Gene Symbol | GeneBank ID | Dorsal retina / FC Injured/normal | Ventral retina/ FC Injured/normal | Function | ||
|---|---|---|---|---|---|---|
| Day 1 | Day 7 | Day 1 | Day 7 | |||
| Cryba1 | NM_013056 | -11.30 * | -16.10* | -3.80 | Constituents of eye lens | |
| Cryba2 | NM_173140 | -6.95 | -10.85 * | -3.50 | Constituents of eye lens | |
| Crygs | NM_173140 | -5.05 | -7.50 * | -3.05 | Constituents of eye lens | |
| Ndrg4 | NM_031967 | -3.20 * | -2.34* | Positive regulation of ERK1 and ERK2 signaling pathway | ||
| Slc6a13 | NM_133623 | -3.63 * | Neurotransmitter activity (Sodium symporter) | |||
| Cxcr6 | NM_001102587 | -2.70* | 1.6 | Chemokine receptor | ||
| N5 | NM_022857 | -2.70* | -2.10* | 1.90 | DNA binding protein | |
| Hbp1 | XM_347266 | -2.50* | Transcriptional regulator | |||
| Gif | NM_017162 | -2.40* | -2.40* | Binds vitamin B12 | ||
| Krtap1-3 | XM_001055744 | -2.40* | Keratin associated protein | |||
| Rhot1 | NM_001107026 | -2.00* | 1.90* | Mitochondrial outer membrane permeabilization | ||
| Lipogenin | NM_145790 | -2.00* | ||||
| Mip | NM_001105719 | -2.80* | Cellular water homeostasis | |||
| Fam134B | NM_001034912 | -2.20* | 1.5* | Long-term survival of nociceptive and autonomic ganglion neurons. | ||
| Ndufb4l1 | XM_001065938 | -2.20* | Oxidation-reduction process | |||
Expression of significantly downregulated genes by fold change ≥ 2. Significance of p-value is indicated by *. Values that may not fall within those parameters are added for the purpose of comparison. Identified and known genes included in the table.