Table 3. Upregulated genes in dorsal and ventral retina following a PT injury.
Gene Symbol | GeneBank ID | Dorsal retina / FC Injured/normal | Ventral retina/ FC Injured/normal | Function | ||
---|---|---|---|---|---|---|
Day 1 | Day 7 | Day 1 | Day 7 | |||
Ecel1 | NM_021776 | 16.20 * | 11.80 * | 2.10 | Proteolysis | |
Timp1 | NM_053819 | 4.60 * | 3.30 * | -2.25 * | Metalloendopeptidase inhibitor activity | |
Mt2A | NM_001137564 | 4.50 * | 4.30 * | Cellular zinc ion homeostasis | ||
CD74 | NM_013069 | 4.10 * | 4.10 * | Activation of MAPK activity | ||
Gfap | NM_017009 | 4.00 * | 3.45 * | -2.20 * | Response to wounding (glia) | |
S100a11 | NM_001004095 | 3.40 * | 2.40* | Calcium ion binding | ||
Gpnmb | NM_133298 | 3.40 * | 2.80 * | Cell adhesion | ||
Tmem47 | NM_001109317 | 3.30 * | 2.40 * | Cell-cell junction | ||
Egr1 | NM_012551 | 3.30 * | 2.80 * | Negative regulation of transcription from RNA polymerase II promoter | ||
Arhgdib | NM_001009600 | 3.20 * | 2.50 * | Rho GDP-dissociation inhibitor activity | ||
H2afy2 | NM_001135807 | 3.20 * | 2.50 * | Nucleosome assembly | ||
Bgn | NM_017087 | 3.10 * | 2.40* | Blood vessel remodelling | ||
Tagln2 | NM_001013127 | 3.00 * | 2.70 * | 1.50* | Tumor suppressor | |
Dhdh | XM_003748855 | 2.90 * | D-xylose catabolic process | |||
Sprr1a | NM_021864 | 2.90 * | 2.10 * | Peptide cross-linking | ||
Atf3 | NM_012912 | 2.90 * | 2.40* | 1.50* | Cell fate determination | |
Tmem108 | XM_008757857 | 2.10* | 2.20* | |||
Rgr | NM_001107299 | 2.30* | 2.30* | Retinal G-protein coupled receptor |
Expression of significantly upregulated genes by fold change ≥ 2. Significance of p-value is indicated by *. Values that may not fall within those parameters are added for the purpose of comparison. Identified and known genes included in the table.