Table 2. Crude and adjusted hazard ratios for the relation of the exposures (SBP and CIMT) and main confounders (DBP, ABI, and SBP) with the outcome (cardiovascular events).
| Model | Variable | Crude HR (95% CI) | Adjusted HR* (95% CI) | |
|---|---|---|---|---|
| 1 | Exposure: SBP per 10 mmHg | 1.11 (1.09, 1.14) | 1.10 (1.07, 1.14) | |
| Confounder: DBP per 10 mmHg | 0.99 (0.94, 1.04) | 0.88 (0.83, 0.94) | ||
| 2 | Exposure: SBP per 10 mmHg | 1.11 (1.09, 1.14) | 1.03 (1.00, 1.06) | |
| Confounder: ABI | 0.20 (0.16, 0.26) | 0.22 (0.18, 0.29) | ||
| 3 | Exposure: CIMT per mm | 2.82 (2.48, 3.20) | 2.10 (1.79, 2.47) | |
| Confounder: SBP per 10 mmHg | 1.11 (1.09, 1.14) | 1.04 (1.01, 1.06) | ||
HR = hazard ratio; SBP = systolic blood pressure; CIMT = carotid intima media thickness; DBP = diastolic blood pressure; ABI = ankle-brachial index at rest.
*Besides the exposure and main confounder shown in the table, each model was further adjusted for the variables age and sex.