Table 2. Anthropometrical and biochemical parameters of non-obese Caucasian individuals according to the presence of NAFLD.
No NAFLD n = 58 |
NAFLD n = 55 |
P< | |
---|---|---|---|
Sex (m/f) | 27/31 | 32/23 | 0.05 |
Age (years) | 42.05±10.16 | 47.59±10.24 | 0.01 |
Body Mass Index (Kg/m2) | 24.87±2.71 | 27.28±2.27 | 0.001 |
Waist Circumference (cm) | 87.65±11.68 | 98.91±9.88 | 0.001 |
Hepatic Triglycerides (%) | 2.37±1.39 | 28.94±13.82 | 0.001 |
Cholesterol (mg/dl) | 192.26±43.30 | 194.54±40.39 | NS |
LDL-C (mg/dl) | 112.86±35.07 | 114.43±36.03 | NS |
HDL-C (mg/dl) | 61.23±14.91 | 51.73±15.14 | 0.01 |
Triglycerides (mg/dl) | 85.81±65.75 | 130.50±70.09 | 0.01 |
Serum AST (IU/L) | 21.86±8.02 | 29.05±11.05 | 0.01 |
Serum ALT (IU/L) | 20.05±6.97 | 41.30±18.14 | 0.001 |
GGT (IU/L) | 27.91±24.23 | 56.19±53.74 | 0.01 |
Glucose (mg/dl) | 94.86±15.44 | 105.89±50.28 | NS |
Fasting serum insulin (μU/ml) | 5.92±2.20 | 12.91±6.90 | 0.001 |
HOMA-IR | 2.47±1.04 | 6.73±4.10 | 0.001 |
TNF-α (ρg/ml) | 150.62±27.41 | 163.32±53.04 | NS |
Adiponectin (μg/ml) | 14.81±8.60 | 7.57±7.06 | 0.001 |
ALT, alanine aminotransferase, AST, aspartate aminotransferase; BMI, body mass index; GGT, gamma-glutamyl transferase; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; LDL-C, low-density lipoprotein cholesterol; NAFLD, non-alcoholic fatty liver disease; NS, non-significant; TNFα, tumor necrosis factor-α. Data are expressed as means ± standard deviation.
P value: the chi-square test for non-continuous variables and the unpaired Student’s two-tailed t-test or nonparametric Mann-Whitney U test, as appropriate, for continuous variables.