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. 2018 Jan 30;12(1):e0006201. doi: 10.1371/journal.pntd.0006201

Fig 4. Production of IL-1β and IL-10 in lungs of BALB/c mice infected by wild-type K. rhinoscleromatis, KR cps-, Kp52Δwzc or Kp52145.

Fig 4

BALB/c mice were infected with 2.107 KR WT, 2.107 KR cps- or 4.108 KR cps- or saline-injected for 6, 24, 48, 72 or 96 hours. Lungs were then homogenized and the pro-inflammatory IL-1β (A) and the anti-inflammatory IL-10 (B) cytokines were measured by ELISA. Data are mean from 6 to 10 mice from three independent experiments. Correlation between production of IL-1β (C) or IL-10 (D) and the amount of bacteria recovered from lungs of mice at 96 hours after injection with saline (control) or infection with 2.107 KR WT, 2.107 KR cps-, 4.108 KR cps-, 109 KR cps-, 109 Kp52Δwzc or 2.104 Kp52145.