Table 3. Comparison of CKRS-treated Brain MRIs in Patients with Brain Metastases treated with CKRS.
* Local control consists of complete response, partial response or stable.
** Local failure = progressive disease all per the response assessment in neuro-oncology brain metastases (RANO-BM) working group imaging outcome determination criteria for brain metastases [3]
*** Radiation necrosis = MRI and histologically-documented only
CKRS = CyberKnife radiosurgery; MRI = magnetic resonance imaging; n = number
| n | (%) | ||
| Brain MRI Response | |||
| Local Control* | 119 | (79.3) | |
| Complete Response | 38 | (25.3) | |
| Partial Response | 56 | (37.3) | |
| Stable | 25 | (16.7) | |
| Local Failure** | 31 | (20.7) | |
| Distal Brain Failure | 83 | (55.3) | |
| Leptomeningeal Disease | 13 | (8.7) | |
| Radiation Necrosis*** | 5 | (3.3) | |