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. 2017 Dec 28;52(3):656–678. doi: 10.3892/ijo.2017.4233

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Copyright: © Handschuh et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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The results of real-time PCR-based expression analysis of 4 genes (NPM1, S100A8, S100A9 and STMN1) in acute myeloid leukemia (AML) compared with healthy volunteers (HV) samples, with the AML divided according to the mutation status of (A) RUNX1/RUNX1T1; (B) NPM1; (C) FLT3; and (D) NPM1 and FLT3 together. The y-axes show relative expression values of a studied gene compared to the reference genes. Each plot contains the ANOVA p-value obtained for a whole test. Pair-wise comparisons with statistically significant differences, verified with a t-test and HSD Tukey test, are indicated by letters and asterisk symbols above each bar. Bars showing the same letter indicate no significant difference (p>0.05). The numbers of asterisks denote the level of statistical significance: ^*p≤0.05, ^**p≤0.01 and ^***p≤0.001.