Table III.
Analysis of biological pathway (WikiPathways) deregulation upon the interaction of normal epithelial NL-20 pleural cells with renal cell cancer cells ACHN.
| Pathway name | Pathway no. | P-value |
|---|---|---|
| Interleukin-6 signaling | WP2704 76915 | 0.04469201 |
| Activation of gene expression by SREBP (SREBF) | WP2706 76917 | 0.006162484 |
| Opioid signaling | WP1978 76919 | 0.051675532 |
| Fc-gamma receptor (FCGR) dependent phagocytosis | WP2719 76936 | 0.006467762 |
| DAG and IP3 signaling | WP2688 76890 | 0.016291482 |
| GPCR ligand binding | WP1825 76977 | 0.030907014 |
| GPCR downstream signaling | WP1824 76910 | 0.0152681 |
| Transcriptional activity of SMAD2-SMAD3-SMAD4 heterotrimer | WP2755 77005 | 0.030645737 |
| Fatty acid, triacylglycerol, and ketone body metabolism | WP1817 77087 | 0.04063944 |
| Generic transcription pathway | WP1822 77033 | 0.016291482 |
Pathways deregulated in NL-20 cells are shown.