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. Author manuscript; available in PMC: 2018 Feb 9.
Published in final edited form as: Nature. 2017 Nov 13;552(7683):110–115. doi: 10.1038/nature24676

Extended Data Table 1.

84 patients undergoing coronary artery bypass grafting donated right atrial biopsies

DEMOGRAPHICS

 Age (years) 60.2 ± 7.2
 Sex (M/F) 69/15
 Race (CH/MY/IN/other) 53/12/16/3
 Height (m) 1.6 ± 0.1
 Weight (kg) 70.3 ± 12.0
 Waist Circumference (cm) 93.6 ± 11.2
 Hip Circumference (cm) 97.0 ± 9.5
 Systolic BP (mmHg) 128.5 ± 17.1
 Diastolic BP (mmHg) 73.0 ± 9.2

MEDICAL HISTORY

 Hypertension (Y/N) 74/8
 Smoking (Y/N/Ex) 12/41/29
 Myocardial infarct (Y/N) 33/40
 Atrial fibrillation* (Y/N) 5/74
 Diabetes (Y/N) 50/34
 Diuretic (Y/N) 8/76
 Beta Blocker (Y/N) 74/10
 Nitrate (Y/N) 52/32
 Insulin (Y/N) 13/71
 Oral anti-diabetic (Y/N) 42/41
 ACE or ARB (Y/N) 46/38
 Statin (Y/N) 80/4
 Calcium antagonist (Y/N) 26/56

ECG DATA

 PR (ms) 174 ± 29
 QRS (ms) 93.8 ± 15.5
 QT (ms) 415.5 ± 35.3
 Heart rate (bpm) 69.0 ± 11.0

BLOOD TESTS

 Hemoglobin (g/L) 13.6 ± 1.6
 Urea (mM/L) 5.7 ± 2.2
 Creatinine (μM/L) 101.1 ± 70.1
 Fasting glucose (mM/L) 7.9 ± 3.5

ECHO DATA

 LVEF (%) 52.3 ± 12.9
 Left atrial area (cm2) 4.1 ± 0.7
 LVIDd (cm) 4.9 ± 0.7
 LVIDs (cm) 3.3 ± 0.8
 E/A Ratio 1.1 ± 0.7

BIOPSY

 Biopsy weight (mg) 94.6 ± 59.5

Categorical data are presented as yes (Y) or no (N), unless otherwise indicated. Echocardiography (Echo) data: left ventricular ejection fraction (LVEF), left ventricular internal diameter in diastole (LVIDd), left ventricular internal diameter in systole (LVIDs), mitral valve inflow measured as ratio of peak velocity flow in early diastole (E) compared to late diastole (A) caused by atrial contraction (E/A) ratio. Atrial fibrillation* refers to any present or previous history of atrial fibrilation. Quantitative data represented as mean ±s.d. CH, Chinese; Ex, ex-smoker; IN, Indian sub- continent; MY, Malaysian.