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. Author manuscript; available in PMC: 2018 Jul 26.
Published in final edited form as: J Am Chem Soc. 2017 Jul 11;139(29):9972–9978. doi: 10.1021/jacs.7b04263

Figure 2.

Figure 2

Synthesis of Mito-CCy and CCy. (i) Triphenylphosphine, acetonitrile, reflux, 24 h, 88%; (ii) 4-(bromomethyl)benzoic acid, acetonitrile, 110 °C, 6 h, 72%; (iii) N,N′-diphenylformamidine, acetic anhydride, 150 °C, 1 h, 87%; (iv) 3, TEA, dichloromethane, 25 °C, 24 h, 46%; (v) propylamine, HATU, TEA, DIPEA, DMF, rt, 24 h, 32%; (vi) 4, HATU, TEA, DIPEA, DMF, rt, 24 h, 34%.