Figure 3. Phosphorylated Tau Pathology for Each Brain Region by CTE Neuropathological Stage.
CTE indicates chronic traumatic encephalopathy; NFT: neurofibrillary tangle, SI: substantia innominata, SN: substantia nigra; LC: locus coeruleus. Cerebellum indicates dentate nucleus of the cerebellum. In each region, 0 = no NFTs (yellow); 1 = 1 NFT per 20× field (orange); 2 = 2 to 3 NFTs per 20× field (amber); and 3 = ≥4 NFTs per 20× field (red). The color scale is based on the distribution of all values, not by each individual stage. Values represent means of phosphorylated tau pathology among participants in each stage.