Table 1.
Demographics (% of patients) | Control (n = 11) | Arginine (n = 11) | t-test/chi square |
---|---|---|---|
Gender | |||
Female (%) | 36.4 | 27.3 | ns |
Male (%) | 63.6 | 72.7 | |
Race | |||
African American (%) | 9.1 | 9.1 | ns |
Asian (%) | 27.3 | 0.0 | ns |
Caucasian (%) | 45.4 | 63.6 | ns |
Unknown (%) | 18.2 | 27.3 | ns |
Ethnicity (% Hispanic/Latino) | 18.2 | 18.2 | ns |
Age (year; mean±SD) | 47.7±12.9 | 61.8±7.9 | −3.08** |
Body mass index (kg/m2; mean±SD) | 24.8±5.4 | 28.7±3.3 | ns |
| |||
Diagnosis (% of patients) | |||
| |||
Malignancy (%) | 63.6 | 81.8 | ns |
Colon Carcinoma (%) | 27.3 | 36.4 | |
Rectal Carcinoma (%) | 36.4 | 45.5 | |
Non-cancerous conditions (%) | 36.4 | 18.2 | ns |
Diverticulitis/colitis | 27.2 | 18.2 | |
Partial obstruction | 9.1 | 0.0 | |
History of chemo-radiation >1 month (%) | 27.3 | 27.3 | ns |
| |||
Surgical procedure (% of patients) | |||
| |||
Segmental colectomy (%) | 36.4 | 45.5 | ns |
Proctectomy (%) | 45.5 | 54.5 | ns |
Small bowel operations (%) | 18.2 | 0.0 | ns |
Laparoscopic (%) | 63.6 | 81.8 | ns |
Open (%) | 36.4 | 18.2 | ns |
Stoma (%) | 36.4 | 45.5 | ns |
| |||
Surgical and anesthetic parameters | |||
| |||
Patient ASA class (median; range) | 2 (2–3) | 3 (2–3) | ns |
Surgery Duration (min; mean±SD) | 183±101 | 159±59 | ns |
Anesthesia Duration (min; mean±SD) | 228±100 | 208±56 | ns |
Blood loss (ml; mean±SD) | 81±61 | 82±60 | ns |
Urine output (ml; mean±SD) | 239±143 | 269±162 | ns |
Fluids | |||
Crystalloids (ml; mean±SD) | 1160±425 | 1261±307 | ns |
Colloids (ml; mean±SD) | 100±211 | 73±168 | ns |
Blood products (ml; mean±SD) | 0 | 0 | ns |
| |||
Postoperative complications1 (% of patients) | |||
| |||
Any complication (%) | 54.5 | 27.3 | ns |
Grade 1 | 0.0 | 9.1 | |
Grade 2 | 27.3 | 0.0 | |
Grade 3 | 27.3 | 18.2 | |
Grade 4 | 0.0 | 0.0 | |
Grade 5 | 0.0 | 0.0 | |
Infection (%) | 36.4 | 18.2 | ns |
Abscess | 9.1 | 18.2 | |
Wound | 18.2 | 0.0 | |
Pouch | 9.1 | 0.0 |
p = 0.007
Clavien-Dindo classification: Grade 1 = minor deteriorations without need of specific treatment, grade 2: treatment with drugs, blood transfusion, or physiotherapy, grade 3: require interventional or operative treatment, grade 4 = life-threatening requiring management in intensive care unit management, grade 5 = death