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. 2018 Feb 5;9:26. doi: 10.3389/fgene.2018.00026

FIGURE 4.

FIGURE 4

Analysis of the nasal cavity proteome. Graphical representations of protein signal distributions (A) reveal the two groups of high protein-abundance data (green curve) and low abundance data. Similarities between proteins and individuals were detected with a hierarchical clustering method in heatmaps using complete linkage and Euclidean distance: (B) the top 5% of highly expressed proteins include, e.g., LCN11, LCN13, OBP1, OBP2, OBP5, OBP8; (B) the top 5% of the most significant sexually dimorphic proteins (p < 0.01) include, e.g., ESP1 and SCGB2B20. There is a notable variation between individuals in protein abundances (B–D). Note that the expression of most lipocalins is non-dimorphic with the exception of LCN11, and the group-B/central MUPs – sMUP9, MUP10, and sMUP17. P ≤ 0.05, ∗∗P ≤ 0.01, ∗∗∗P ≤ 0.001).