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. 2018 Feb 5;9:158. doi: 10.3389/fimmu.2018.00158

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Copyright © 2018 Hwang, Shin, Yang, Jung, Lee and Shin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heat maps representing cytokine and chemokine concentrations in the inflammatory immune response and microglia phenotypes. Transcript levels of inflammatory and anti-inflammatory cytokines as well as microglia phenotype markers were measured in Toxoplasma gondii-infected mouse brains using microarray analysis. Each row of the heat map represents cytokines related with inflammatory and anti-inflammatory responses (A) as well as microglia phenotype markers related with the M1-type and M2-type (B). Each column represents infection times from week 0 to 12 postinfection. The color scale corresponds to the relative expression of the cytokine for the minimum (−3) and maximum (+3) of all values.