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. 2018 Feb 5;9:127. doi: 10.3389/fmicb.2018.00127

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Copyright © 2018 Kumaran, Taha, Yi, Ramirez-Arcos, Diallo, Carli and Abdelbary.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Viable S. aureus ATCC 35556 counts 48 h following exposure to phage SATA-8505 and different concentrations of antibiotics that inhibit translation; (A) tetracycline and (B) linezolid. The treatment scenarios: antibiotic alone, phage alone, phage and antibiotic simultaneously, phage first then followed by antibiotic, or antibiotic first followed by phage. Synergistic (S) and additive (A) interactions have been indicated. Bacterial cells treated with MH-CA alone served as a control (cell). N = 3 ±SD.